Vice President, Transformational & Major Giving – THE PRINCESS MARGARET CANCER FOUNDATION

Established in 1982, The Princess Margaret Cancer Foundation (The PMCF) has been setting daring and audacious goals with a mindset that is driven by our culture and passion for the cause. We have pioneered many successful fundraising programs, including our world-leading Princess Margaret Home Lottery, and some of the world’s largest peer-to-peer cancer fundraising events, and have a sophisticated Major and Estate Giving program.

Moving forward, we are excited to introduce this new Vice President role to grow and lead our efforts in transformational-level philanthropy. Reporting to the President & Chief Executive Officer and serving as a key member of the Foundation’s Senior Leadership Team, the Vice President, Transformational & Major Giving will be the designated lead, internal champion, and resource for transformational ($10M+), major ($50k-$9.99M) and planned and estate gifts.

We are seeking an experienced, forward-thinking senior leader to join the Foundation, providing leadership to a team of talented fundraising professionals, and driving an ambitious fundraising plan as we prepare to launch a historic, comprehensive fundraising campaign for The Princess Margaret. Salary Range:  $250,000 – $325,000

Posted On:  November 10, 2023

Closing On:  December 22, 2023

Location:  Toronto, Ontario

Employment Type:  Full Time

Level:  Management

Salary Range:  $250,000 – $325,000


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Vice President, Transformational & Major Giving

Cancer touches everyone. With cancer stubbornly remaining the number one cause of death for Canadians, and the second leading cause worldwide, and cases expected to double in the next 20 years, our top priority must be to accelerate cancer research and care.

At The Princess Margaret, we have a bold vision to Conquer Cancer In Our Lifetime.  

As one of the world’s top five cancer research centres, Princess Margaret Cancer Centre is known for its game-changing scientific discoveries and exceptional patient care. And the Foundation’s role is to support, enable, and accelerate this work.

There are many signs that the future is bright. Our dedicated community, combined with the excellence, determination, and creative thinking of the team at the Princess Margaret Cancer Centre, is building a movement around cancer. Together, we can all make a profound impact, prolonging lives and giving people more time with their loved ones, both here and around the important advances.

With the generous backing of a passionate community of supporters, we’re transforming the cancer experience, giving real hope to cancer patients in Canada and around the world. This past fiscal year the Foundation raised $284 million, our highest revenue ever, and granted $144.9 million to the Princess Margaret Cancer Centre to help turn this vision into a future reality. These crucial funds helped to drive world-class cancer research forward and set new standards of care.

With the power of our movement, we will achieve our vision to Conquer Cancer In Our Lifetime. Every donation made today accelerates cancer research, improving and prolonging lives tomorrow.

Virtually all academic healthcare fundraising is characterized by an organization’s success in attracting large transformational and major gift donors to fuel a campaign. While The PMCF has attracted transformational gifts in the past and has a well-established major gifts program, there is capacity for it to grow significantly and indeed will be integral to a successful campaign.

We are seeking an individual with proven transformational gift experience and an entrepreneurial spirit to help us grow new 7 and 8-figure gift commitments to The PMCF and its campaign priorities. The new Vice President will also work directly with select transformational donor prospects, as well as closely engage with the Campaign Chair(s) and other volunteers, the Foundation CEO and senior leaders, and with UHN leadership and cancer centre colleagues to successfully achieve our ambitious fundraising goals.

The Foundation has a strong team of major gift fundraisers, with a broad range of experience in the sector. The new Vice President will enhance our bench strength by being a role model and coach the team on major and transformational giving.

It is also important that we increase the volume of major gift discussions significantly, particularly given their importance to the campaign. Having a dedicated resource with extensive experience in this area will help address the anticipated volumes and set ambitious donor call activity for the major gifts staff. They will be responsible to build upon the transitional gift strategy and ensure alignment with the 5-year strategic plan.

The PMCF offers a competitive compensation package including base salary, incentive pay, health benefits, and participation in the Healthcare of Ontario Pension Plan (HOOPP). The hiring range for this role is $250,000 – $325,000 plus incentive compensation of up to 20%.

This position is based at the Foundation offices at 700 University Avenue in Toronto. The Foundation currently offers a hybrid work environment with Tuesday, Thursday, and one other day per week in office, or as required subject to business needs. Please note that the role requires willingness and availability to work flexible hours, including some after-hours work and weekends from time to time.



The Vice President, Transformational & Major Giving will focus their time, attention, and efforts in the following areas:



Strategic Leadership




We believe that how we work together is as important as what we do. When we make choices and take actions that align with our values, we achieve greater success, and our lives at work are happier and more meaningful.

The people of the PMCF choose to create a culture that supports Collaboration, Accountability, Respect & Excellence (CARE). Essential to these values is a commitment to IDEAA: Inclusion, Diversity, Equity, Accessibility and Anti-Racism.



Welcome to the Home of Cancer Breakthroughs!  We have a long list of world firsts and we will not stop until we stop cancer. Below we’ve listed just a few of the major breakthroughs driven by science and creativity at The Princess Margaret:

We revolutionized the world’s understanding of cancer. Princess Margaret scientists Till and McCulloch’s discovery of the stem cell in 1963 was a revolutionary moment in cancer research and care. The cell’s ability to renew and repair tissues in the human body laid the foundations for regenerative medicine around the world.

We pioneered immunotherapy, a less toxic alternative to chemotherapy. Dr. Tak Mak cloned the T-cell receptor in 1983, a discovery that paved the way for more effective and less toxic cancer treatments through immunotherapy.

We developed a blood test with the potential to change how cancer is detected. In 2018, Drs. Daniel De Carvalho and Scott Bratman developed a simple blood test to detect different kinds of cancer and their location in the body, potentially diminishing the need for biopsies and allowing doctors to detect cancer earlier, when it’s more curable.

We learned that cancer cells can hide. In 2021, Dr. Catherine O’Brien discovered that cancer cells can hibernate like bears to survive chemotherapy and other anti-cancer drugs. This important finding is helping researchers discover new treatments that prevent cancer cells from surviving chemo and causing a relapse.

We’re extending the lives of glioblastoma patients. Drs. Farshad Nassiri and Gelareh Zadeh published results of a clinical trial showing a new treatment for recurrent glioblastoma, a challenging cancer, is well tolerated and extends patients’ lives.

We’re improving the effectiveness of immunotherapy. Dr. Naoto Hirano has pioneered novel approaches to improve the effectiveness of immunotherapy and make it available to a wider range of patients. His new (CAR) T-cell approach is currently in clinical trials.

Hodgkin Lymphoma used to be a death sentence. Then we discovered it was curable. In 1950, Dr. Vera Peters discovered Hodgkin lymphoma could be cured with extended field radiation.

We find what can’t be seen. In 2014, Dr. John Dick discovered some patients are pre-disposed to leukemia and cardiovascular diseases, helping to identify patients at risk of cancer and heart disease before patients even show symptoms of these illnesses.

We use new tech to see cancer in a new light. In 2014, Dr. Gang Zheng developed unique nanotechnology to make tumours glow, giving patients the potential to receive information in real-time on how their cancer is responding to treatment.

We are home to one of the world’s largest clinical trials programs. We test more new therapies to benefit cancer patients around the world.

We can predict who will respond to immunotherapy. Which patients will respond to cancer treatment has long perplexed doctors, and with potentially devastating consequences for patients and their loved ones. Drs. Lillian Siu, Scott Bratman, and Trevor Pugh have demonstrated the ability of early “liquid biopsy” DNA blood testing to predict immunotherapy response across many cancer types.

We give more patients more hope. We have performed over 3,000 stem cell transplants through the Hans Messner Allogenic Stem Cell Transplant program — the largest of its kind in Canada.


Application Process

KCI Search + Talent has been retained to conduct this search on behalf of The Princess Margaret Cancer Foundation. For more information about this opportunity, candidates are invited to contact Tara George or Ellie Rusonik via email at

To be considered for the role, candidates are invited to send a resume and letter of interest to the email address listed above. Please note that candidate submissions will be reviewed as they arrive, so early inquiry and submission is encouraged. All inquiries and applications will be held in strict confidence.

To view full position brief, please visit

The PMCF aims to make our recruitment and selection processes as accessible as possible and will provide accommodations as required for applicants with disabilities, in accordance with the Accessibility for Ontarians with Disabilities Act. If you require any accommodations at any point during the application and hiring process, please contact our search firm partners at KCI directly.

Recognizing the strength and value of diverse perspectives and lived experiences in representing the communities served by The Princess Margaret, we encourage applications from Indigenous, Black and racialized people, women, people with disabilities, and people of diverse sexual and gender identities.

Vaccines (COVID-19 and others) are a job requirement unless you have an exemption on a medical ground pursuant to the Ontario Human Rights Code.